Sarin

Sarin^[1]
	S-Sarin
Names
Pronunciation	/ˈsɑːrɪn/
	Preferred IUPAC name Propan-2-yl methylphosphonofluoridate
	Other names (RS)-O-Isopropyl methylphosphonofluoridate; IMPF;; GB;; 2-(Fluoro-methylphosphoryl)oxypropane;; Phosphonofluoridic acid, P-methyl-, 1-methylethyl ester; EA-1208; TL-1618; T-144
Identifiers
CAS Number	107-44-8 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:75701 ;
ChEMBL	ChEMBL509554 ;
ChemSpider	7583 ;
PubChem CID	7871;
UNII	B4XG72QGFM ;
CompTox Dashboard (EPA)	DTXSID0042371 ;
	InChI InChI=1S/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3 Key: DYAHQFWOVKZOOW-UHFFFAOYSA-N ; InChI=1/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3; InChI=1/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3 Key: DYAHQFWOVKZOOW-UHFFFAOYAY;
	SMILES FP(=O)(OC(C)C)C;
Properties
Chemical formula	C4H10FO2P
Molar mass	140.094 g·mol−1
Appearance	Clear colourless liquid, brownish if impure
Odor	Odourless in pure form. Impure sarin can smell like mustard or burned rubber.
Density	1.0887 g/cm3 (25 °C); 1.102 g/cm3 (20 °C)
Melting point	−56 °C (−69 °F; 217 K)
Boiling point	158 °C (316 °F; 431 K)
Solubility in water	Miscible
log P	0.30
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Extremely lethal cholinergic agent.
	GHS labelling:
Pictograms
NFPA 704 (fire diamond)	4 1 1
Threshold limit value (TLV)	0.00003 mg/m3 (TWA), 0.0001 mg/m3 (STEL)
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	39 μg/kg (intravenous, rat)
	NIOSH (US health exposure limits):
IDLH (Immediate danger)	0.1 mg/m3
Safety data sheet (SDS)	Lethal Nerve Agent Sarin (GB)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Sarin (NATO designation GB [short for G-series, "B"]) is an extremely toxic organophosphorus compound.^[4] A colourless, odourless liquid, it is used as a chemical weapon due to its extreme potency as a nerve agent. Exposure can be lethal even at very low concentrations, where death can occur within one to ten minutes after direct inhalation of a lethal dose,^[5]^[6] due to suffocation from respiratory paralysis, unless antidotes are quickly administered.^[4] People who absorb a non-lethal dose and do not receive immediate medical treatment may suffer permanent neurological damage.^{[citation needed]}

Sarin is widely considered a weapon of mass destruction. Production and stockpiling of sarin was outlawed as of April 1997 by the Chemical Weapons Convention of 1993, and it is classified as a Schedule 1 substance.

^ "Material Safety Data Sheet – Lethal Nerve Agent Sarin (GB)". 103d Congress, 2d Session. United States Senate. May 25, 1994. Retrieved November 6, 2004.
^ "Sarin". National Institute of Standards and Technology. Retrieved March 27, 2011.
^ "Substance Name: Sarin". ChemIDplus. U.S. National Library of Medicine, National Institutes of Health. Retrieved January 19, 2020.
^ ^a ^b Sarin (GB). Emergency Response Safety and Health Database. National Institute for Occupational Safety and Health. Accessed April 20, 2009.
^ Anderson K (September 17, 2013). A Poisonous Affair: America, Iraq, and the Gassing of Halabja review of A Poisonous Affair: America, Iraq, and the Gassing of Halabja by Joost R. Hiltermann (Cambridge UP 2007). Lawfare: Hard National Security Choices (Report). Retrieved December 30, 2015. ... death can occur within one minute of direct inhalation as the lung muscles are paralyzed.
^ Smith M (August 26, 2002). "Saddam to be target of Britain's 'E-bomb'". The Daily Telegraph. p. A18. Retrieved December 30, 2015. The nerve agents sarin and VX. Colourless and tasteless, they cause death by respiratory arrest in one to 15 minutes.

[1] "Material Safety Data Sheet – Lethal Nerve Agent Sarin (GB)". 103d Congress, 2d Session. United States Senate. May 25, 1994. Retrieved November 6, 2004.

[2] "Sarin". National Institute of Standards and Technology. Retrieved March 27, 2011.

[Substance_Name:_Sarin-3] "Substance Name: Sarin". ChemIDplus. U.S. National Library of Medicine, National Institutes of Health. Retrieved January 19, 2020.

[niosh-4] Sarin (GB). Emergency Response Safety and Health Database. National Institute for Occupational Safety and Health. Accessed April 20, 2009.

[5] Anderson K (September 17, 2013). A Poisonous Affair: America, Iraq, and the Gassing of Halabja review of A Poisonous Affair: America, Iraq, and the Gassing of Halabja by Joost R. Hiltermann (Cambridge UP 2007). Lawfare: Hard National Security Choices (Report). Retrieved December 30, 2015. ... death can occur within one minute of direct inhalation as the lung muscles are paralyzed.

[6] Smith M (August 26, 2002). "Saddam to be target of Britain's 'E-bomb'". The Daily Telegraph. p. A18. Retrieved December 30, 2015. The nerve agents sarin and VX. Colourless and tasteless, they cause death by respiratory arrest in one to 15 minutes.

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