William Twisse (1578 near Newbury, England – 20 July 1646) was a prominent English clergyman and theologian. He was named Prolocutor of the Westminster Assembly in an Ordinance dated 12 June 1643,[1] putting him at the head of the churchmen of the Commonwealth. He was described by a Scottish member, Robert Baillie, as "very good, beloved of all, and highlie esteemed; but merelie bookish."[2]