Back العامل الحادي عشر Arabic Faktor XI BS Factor XI Catalan Faktor XI Czech F11 CY Plasma Thromboplastin Antecedent German Factor XI English Factor de coagulación XI Spanish Tekijä XI Finnish Facteur Rosenthal French
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| PDB 1xx9 | |
F11
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| Identificadores | |
| Símbolo | F11 |
| Símbolos alt. | FXI, factor de coagulación XI, PTA |
| Entrez | 2160 |
| OMIM | |
| RefSeq | NP_000119 |
| UniProt | P03951 |
| Outros datos | |
| Locus | Cr. 4 q35.2:(186.27 – 186.29 Mb) |
O factor XI ou antecedente de tromboplastina plasmática é o cimóxeno do factor XIa, un dos encimas da fervenza da coagulación do sangue. Como moitos outros factores de coagulación, é unha serina protease. Nos humanos, o factor XI está codificado no xene F11 do cromosoma 4.[1][2][3][4]
- ↑ Fujikawa K, Chung DW, Hendrickson LE, Davie EW (May 1986). "Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein". Biochemistry 25 (9): 2417–24. PMID 3636155. doi:10.1021/bi00357a018.
- ↑ Asakai R, Davie EW, Chung DW (Nov 1987). "Organization of the gene for human factor XI". Biochemistry 26 (23): 7221–8. PMID 2827746. doi:10.1021/bi00397a004.
- ↑ Kato A, Asakai R, Davie EW, Aoki N (1989). "Factor XI gene (F11) is located on the distal end of the long arm of human chromosome 4". Cytogenetics and Cell Genetics 52 (1-2): 77–8. PMID 2612218. doi:10.1159/000132844.
- ↑ Buetow KH, Shiang R, Yang P, Nakamura Y, Lathrop GM, White R, Wasmuth JJ, Wood S, Berdahl LD, Leysens NJ (May 1991). "A detailed multipoint map of human chromosome 4 provides evidence for linkage heterogeneity and position-specific recombination rates". American Journal of Human Genetics 48 (5): 911–25. PMC 1683054. PMID 1673289.