Diuretik hemat kalium

Diuretik hemat kalium atau antikaliuretik^[1] mengacu pada obat yang menyebabkan diuresis tanpa menyebabkan hilangnya kalium dalam urin.^[2] Obat ini biasanya digunakan sebagai tambahan dalam penanganan hipertensi, sirosis, dan gagal jantung kongestif.^[3] Antagonis aldosteron steroid juga dapat digunakan untuk pengobatan hiperaldosteronisme primer. Spironolakton, suatu antagonis steroid aldosteron, juga digunakan dalam pengelolaan hirsutisme wanita dan jerawat akibat PCOS atau penyebab lainnya.^[4]^[5]

^ Knepper, Mark A.; Kleyman, Thomas; Gamba, Gerardo (2005), "Diuretics: Mechanisms of Action", Hypertension, Elsevier, hlm. 638–652, doi:10.1016/b978-0-7216-0258-5.50152-6, ISBN 978-0-7216-0258-5, diakses tanggal 2024-03-24
^ Rose BD (February 1991). "Diuretics". Kidney Int. 39 (2): 336–52. doi:10.1038/ki.1991.43 . PMID 2002648.
^ Weber KT, Villarreal D (January 1993). "Aldosterone and antialdosterone therapy in congestive heart failure". The American Journal of Cardiology. 71 (3): A3–A11. doi:10.1016/0002-9149(93)90238-8. PMID 8422002.
^ Martin KA, Anderson RB, et al. (1 April 2018). "Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society* Clinical Practice Guideline". The Journal of Clinical Endocrinology & Metabolism. 103 (4): 1233–1257. doi:10.1210/jc.2018-00241 . PMID 29522147.
^ Grandhi R, Alikhan A (2017). "Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study". Dermatology. 233 (2–3): 141–144. doi:10.1159/000471799 . PMID 28472793.

[1] Knepper, Mark A.; Kleyman, Thomas; Gamba, Gerardo (2005), "Diuretics: Mechanisms of Action", Hypertension, Elsevier, hlm. 638–652, doi:10.1016/b978-0-7216-0258-5.50152-6, ISBN 978-0-7216-0258-5, diakses tanggal 2024-03-24

[pmid2002648-2] Rose BD (February 1991). "Diuretics". Kidney Int. 39 (2): 336–52. doi:10.1038/ki.1991.43 . PMID 2002648.

[3] Weber KT, Villarreal D (January 1993). "Aldosterone and antialdosterone therapy in congestive heart failure". The American Journal of Cardiology. 71 (3): A3–A11. doi:10.1016/0002-9149(93)90238-8. PMID 8422002.

[4] Martin KA, Anderson RB, et al. (1 April 2018). "Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society* Clinical Practice Guideline". The Journal of Clinical Endocrinology & Metabolism. 103 (4): 1233–1257. doi:10.1210/jc.2018-00241 . PMID 29522147.

[5] Grandhi R, Alikhan A (2017). "Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study". Dermatology. 233 (2–3): 141–144. doi:10.1159/000471799 . PMID 28472793.

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