| SRY |
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| Estruturas disponíveis |
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| PDB | Pesquisa Human UniProt: PDBe RCSB |
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| Identificadores |
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| Nomes alternativos | SRY |
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| IDs externos | OMIM: 480000 HomoloGene: 48168 GeneCards: SRY |
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| Ontologia genética |
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| Função molecular | • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
• transcription factor binding
• calmodulin binding
• transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
• DNA binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
• GO:0001948, GO:0016582 ligação a proteínas plasmáticas
• GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific
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| Componente celular | • citoplasma
• nuclear speck
• cariolinfa
• núcleo celular
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| Processo biológico | • diferenciação celular
• GO:0009373 regulation of transcription, DNA-templated
• sex differentiation
• transcription, DNA-templated
• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated
• positive regulation of male gonad development
• male sex determination
• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
• GO:1901227 negative regulation of transcription by RNA polymerase II
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• central nervous system development
• GO:1901313 positive regulation of gene expression
• diferenciação neural
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| Sources:Amigo / QuickGO |
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| Wikidata |
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O gene SRY (do inglês sex-determining region Y) é a região do cromossomo Y que determina o desenvolvimento dos genitais masculinos nos mamíferos térios (marsupiais e placentários).[2]
