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Radical surgery

Radical surgery, also called radical dissection, is a surgery that is more extensive than "conservative" surgery in somewhat manner.[1]

When it comes to surgical oncology, radical surgery is surgery involve removing both a tumor and any metastases for diagnostic motive or treatment purposes.[2] It implies that it consists removal of a tumor or mass and ancillary lymph nodes that may drain the mass, as in radical mastectomy.[3]

Immunohistochemistry with SOX10 (staining the cell nuclei of melanocytes) of lentigo maligna, showing malignant melanocytes all the way to the resection margin (inked in yellow, at left), conferring a diagnosis of a not radically removed lesion.

Whilst in histopathology, radicality of tumor excisions is defined as the absence of tumor cells in a certain resection margin, with the specific margin width varying by tumor type and local guidelines.[4]

  1. ↑ "Radical Surgery - an overview | ScienceDirect Topics". www.sciencedirect.com. Retrieved 2021-11-21.
  2. ↑ "radical surgery". TheFreeDictionary.com. Retrieved 2021-11-21.
  3. ↑ "radical dissection". TheFreeDictionary.com. Retrieved 2021-11-21.
  4. ↑ Schlitter, Anna Melissa; Esposito, Irene (2010-11-25). "Definition of Microscopic Tumor Clearance (R0) in Pancreatic Cancer Resections". Cancers. 2 (4): 2001–2010. doi:10.3390/cancers2042001. ISSN 2072-6694. PMC 3840457. PMID 24281214.

Radical surgery

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