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Ceruloplasmina
A ceruloplasmina é un encima ferroxidase que nos humanos está codificado polo xene CP situado no cromosoma 3.[1][2][3][4]
A ceruloplasmina é a principal proteína transportadora de cobre no sangue, e ademais ten un papel no metabolismo do ferro. Foi descrita en 1948.[5] Outra proteína chamada hefaestina ten unha grande homoloxía coa ceruloplasmina, e participa tamén no metabolismo do ferro e probablemente no do cobre.
- ↑ Takahashi N, Ortel TL, Putnam FW (January 1984). "Single-chain structure of human ceruloplasmin: the complete amino acid sequence of the whole molecule". Proc. Natl. Acad. Sci. U.S.A. 81 (2): 390–4. PMC 344682. PMID 6582496. doi:10.1073/pnas.81.2.390.
- ↑ Koschinsky ML, Funk WD, van Oost BA, MacGillivray RT (July 1986). "Complete cDNA sequence of human preceruloplasmin". Proc. Natl. Acad. Sci. U.S.A. 83 (14): 5086–90. PMC 323895. PMID 2873574. doi:10.1073/pnas.83.14.5086.
- ↑ Royle NJ, Irwin DM, Koschinsky ML, MacGillivray RT, Hamerton JL (May 1987). "Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively". Somat. Cell Mol. Genet. 13 (3): 285–92. PMID 3474786. doi:10.1007/BF01535211.
- ↑ OMIM Ceruloplasmin ; CP
- ↑ Holmberg CG, Laurell C-B (1948). "Investigations in serum copper. II. Isolation of the Copper containing protein, and a description of its properties". Acta Chem Scand 2: 550–56. doi:10.3891/acta.chem.scand.02-0550.
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