Kaspaza-10

Kaspaza-10
Identifikatori
Aliasi	CASP10
Vanjski ID-jevi	OMIM: 601762 HomoloGene: 50038 GeneCards: CASP10
Lokacija gena (čovjek)
Hrom.	Hromosom 2 (čovjek)
Kraj	201,229,428 bp
Obrazac RNK ekspresije
	; ; ; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• death effector domain binding; • GO:0070122 peptidase activity; • cysteine-type peptidase activity; • GO:0001948, GO:0016582 vezivanje za proteine; • hydrolase activity; • ubiquitin protein ligase binding; • cysteine-type endopeptidase activity involved in execution phase of apoptosis; • cysteine-type endopeptidase activity; • cysteine-type endopeptidase activity involved in apoptotic signaling pathway; • cysteine-type endopeptidase activity involved in apoptotic process;
Ćelijska komponenta	• ripoptosome; • citosol; • CD95 death-inducing signaling complex; • citoplazma;
Biološki proces	• positive regulation of I-kappaB kinase/NF-kappaB signaling; • apoptotic signaling pathway; • cell surface receptor signaling pathway; • Proteoliza; • GO:0097285 apoptoza; • regulation of apoptotic process; • execution phase of apoptosis; • activation of cysteine-type endopeptidase activity involved in apoptotic process;
	Izvori:Amigo / QuickGO
Ortolozi
	843
	n/a
	ENSG00000003400
	n/a
	Q92851
	n/a
NM_001206524; NM_001206542; NM_001230; NM_001306083; NM_032974;
	NM_032976; NM_032977
	n/a
NP_001193453; NP_001193471; NP_001221; NP_001293012; NP_116756;
	NP_116758; NP_116759
	n/a
	Wikipodaci
Pogledaj/uredi – čovjek

Kaspaza-10 jest enzim koji je kod ljudi kodiran genom CASP10 sa hromosoma 2.^[3]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000003400 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES (oktobar 1996). "In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains". Proc Natl Acad Sci USA. 93 (15): 7464–9. Bibcode:1996PNAS...93.7464F. doi:10.1073/pnas.93.15.7464. PMC 38767. PMID 8755496.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000003400 - Ensembl, maj 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8755496-3] Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES (oktobar 1996). "In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains". Proc Natl Acad Sci USA. 93 (15): 7464–9. Bibcode:1996PNAS...93.7464F. doi:10.1073/pnas.93.15.7464. PMC 38767. PMID 8755496.

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[2]

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Kaspaza-10

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