ParaHoxozoa (atau Parahoxozoa ) adalah klad haiwan yang terdiri daripada Bilateria , Placozoa , dan Cnidaria .[ 1] Hubungan klad ini berbanding dua garis keturunan haiwan yang lain, Ctenophora dan Porifera , masih diperdebatkan. Beberapa kajian filogenomik telah mengemukakan bukti yang menyokong Ctenophora sebagai saudara kepada Parahoxozoa dan Porifera sebagai kumpulan saudara kepada haiwan yang lain (contohnya, [ 2] [ 3] [ 4] ). Kajian lain telah mengemukakan bukti yang menyokong Porifera sebagai saudara kepada Parahoxozoa dan Ctenophora sebagai kumpulan saudara kepada haiwan yang lain (contohnya, [ 5] [ 6] [ 7] ). Mereka mendapati bahawa sistem saraf sama ada berkembang secara bebas dalam ctenophora dan parahoxozoa,[ 8] atau telah hilang secara sekunder dalam porifera.[ 9] Jika ctenophora dianggap sebagai yang pertama berpisah, Eumetazoa kadangkala digunakan sebagai sinonim untuk ParaHoxozoa.[ 10]
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^ Pick, K. S.; Philippe, H.; Schreiber, F.; Erpenbeck, D.; Jackson, D. J.; Wrede, P.; Wiens, M.; Alie, A.; Morgenstern, B.; Manuel, M.; Worheide, G. (2010). "Improved Phylogenomic Taxon Sampling Noticeably Affects Nonbilaterian Relationships" . Molecular Biology and Evolution . 27 (9): 1983–1987. doi :10.1093/molbev/msq089 . ISSN 0737-4038 . PMC 2922619 . PMID 20378579 .
^ Feuda, Roberto; Dohrmann, Martin; Pett, Walker; Philippe, Hervé; Rota-Stabelli, Omar; Lartillot, Nicolas; Wörheide, Gert; Pisani, Davide (2017). "Improved Modeling of Compositional Heterogeneity Supports Sponges as Sister to All Other Animals" . Current Biology . 6 (24): 3864–3870.e4. Bibcode :2017CBio...27E3864F . doi :10.1016/j.cub.2017.11.008 . hdl :11572/302898 . PMID 29199080 .
^ Simion, Paul; Philippe, Hervé; Baurain, Denis; Jager, Muriel; Richter, Daniel J.; Franco, Arnaud Di; Roure, Béatrice; Satoh, Nori; Quéinnec, Éric (3 April 2017). "A Large and Consistent Phylogenomic Dataset Supports Sponges as the Sister Group to All Other Animals" (PDF) . Current Biology (Submitted manuscript). 27 (7): 958–967. Bibcode :2017CBio...27..958S . doi :10.1016/j.cub.2017.02.031 . ISSN 0960-9822 . PMID 28318975 . S2CID 4560353 .
^ Whelan, Nathan V.; Kocot, Kevin M.; Moroz, Leonid L.; Halanych, Kenneth M. (2015). "Error, signal, and the placement of Ctenophora sister to all other animals" . Proceedings of the National Academy of Sciences . 112 (18): 5773–5778. Bibcode :2015PNAS..112.5773W . doi :10.1073/pnas.1503453112 . ISSN 0027-8424 . PMC 4426464 . PMID 25902535 .
^ Borowiec, Marek L.; Lee, Ernest K.; Chiu, Joanna C.; Plachetzki, David C. (2015). "Extracting phylogenetic signal and accounting for bias in whole-genome data sets supports the Ctenophora as sister to remaining Metazoa" . BMC Genomics . 16 (1): 987. doi :10.1186/s12864-015-2146-4 . ISSN 1471-2164 . PMC 4657218 . PMID 26596625 .
^ Whelan, Nathan V.; Kocot, Kevin M.; Moroz, Tatiana P.; Mukherjee, Krishanu; Williams, Peter; Paulay, Gustav; Moroz, Leonid L.; Halanych, Kenneth M. (2017). "Ctenophore relationships and their placement as the sister group to all other animals" . Nature Ecology & Evolution . 1 (11): 1737–1746. Bibcode :2017NatEE...1.1737W . doi :10.1038/s41559-017-0331-3 . ISSN 2397-334X . PMC 5664179 . PMID 28993654 .
^ Moroz, Leonid L.; Kocot, Kevin M.; Citarella, Mathew R.; Dosung, Sohn; Norekian, Tigran P.; Povolotskaya, Inna S.; Grigorenko, Anastasia P.; Dailey, Christopher; Berezikov, Eugene; Buckley, Katherine M.; Ptitsyn, Andrey; Reshetov, Denis; Mukherjee, Krishanu; Moroz, Tatiana P.; Bobkova, Yelena; Yu, Fahong; Kapitonov, Vladimir V.; Jurka, Jerzy; Bobkov, Yuri V.; Swore, Joshua J.; Girardo, David O.; Fodor, Alexander; Gusev, Fedor; Sanford, Rachel; Bruders, Rebecca; Kittler, Ellen; Mills, Claudia E.; Rast, Jonathan P.; Derelle, Romain; Solovyev, Victor V.; Kondrashov, Fyodor A.; Swalla, Billie J.; Sweedler, Jonathan V.; Rogaev, Evgeny I.; Halanych, Kenneth M.; Kohn, Andrea B. (2014). "The ctenophore genome and the evolutionary origins of neural systems" . Nature . 510 (7503): 109–114. Bibcode :2014Natur.510..109M . doi :10.1038/nature13400 . ISSN 0028-0836 . PMC 4337882 . PMID 24847885 .
^ Ryan, J. F.; Pang, K.; Schnitzler, C. E.; Nguyen, A.-D.; Moreland, R. T.; Simmons, D. K.; Koch, B. J.; Francis, W. R.; Havlak, P.; Smith, S. A.; Putnam, N. H.; Haddock, S. H. D.; Dunn, C. W.; Wolfsberg, T. G.; Mullikin, J. C.; Martindale, M. Q.; Baxevanis, A. D. (2013). "The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution" . Science . 342 (6164): 1242592. doi :10.1126/science.1242592 . ISSN 0036-8075 . PMC 3920664 . PMID 24337300 .
^ Erives, Albert; Fritzsch, Bernd (2020). "A Screen for Gene Paralogies Delineating Evolutionary Branching Order of Early Metazoa" . G3: Genes, Genomes, Genetics . 10 (2): 811–826. doi :10.1534/g3.119.400951 . ISSN 2160-1836 . PMC 7003098 . PMID 31879283 .