Our website is made possible by displaying online advertisements to our visitors.
Please consider supporting us by disabling your ad blocker.

Responsive image

Tamsulosin

Tamsulosin
Clinical data
Pronunciation/tæmˈsuːləsɪn/[1]
tam-SOO-lə-sin
Trade namesFlomax, others
AHFS/Drugs.comMonograph
MedlinePlusa698012
License data
Pregnancy
category
  • AU: B2
Routes of
administration		By mouth
Drug classα1 blocker
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability100% (by mouth)
MetabolismLiver
Elimination half-life9–13 hours
Excretion76% Kidney
Identifiers
  • (R)-5-(2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzene-1-sulfonamide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.109.780 Edit this at Wikidata
Chemical and physical data
FormulaC20H28N2O5S
Molar mass408.51 g·mol−1
3D model (JSmol)
  • CCOc1ccccc1OCCN[C@@H](C)Cc1ccc(OC)c(c1)S(=O)(=O)N
  • InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1 checkY
  • Key:DRHKJLXJIQTDTD-OAHLLOKOSA-N checkY
  (verify)
Tamsulosin – ARISTO Pharma – 0.4 mg prolonged-release tablets – Urologikum

Tamsulosin, sold under the brand names including Flomax and Contiflo, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones.[6][7][8] The evidence for benefit with a kidney stone is better when the stone is larger.[8] Tamsulosin is taken by mouth.[6]

Common side effects include dizziness, headache, insomnia, nausea, blurry vision, and sexual problems.[9][6] Other side effects may include feeling lightheaded with standing due to changes in blood pressure, and angioedema.[9] Tamsulosin is an alpha blocker and works by relaxing muscles in the prostate.[10] Specifically it is an α1-adrenergic receptor blocker.[6]

Tamsulosin was approved for medical use in the United States in 1997.[6] It is available as a generic medication.[9] In 2022, it was the twentieth most commonly prescribed medication in the United States, with more than 25 million prescriptions.[11][12]

  1. ^ "Tamsulosin". Merriam-Webster.com Dictionary. Merriam-Webster.
  2. ^ "Product monograph brand safety updates". Health Canada. February 2024. Retrieved 24 March 2024.
  3. ^ "Flomaxtra XL, 400 micrograms, film-coated prolonged-release tablet – Summary of Product Characteristics (SmPC)". (emc). 12 November 2019. Retrieved 2 December 2021.
  4. ^ "Faramsil 400 microgram Prolonged-release Tablets – Summary of Product Characteristics (SmPC)". (emc). 4 November 2020. Retrieved 2 December 2021.
  5. ^ "Flomax– tamsulosin hydrochloride capsule". DailyMed. Retrieved 2 December 2021.
  6. ^ a b c d e "Tamsulosin Hydrochloride Monograph for Professionals". Drugs.com. AHFS. Retrieved 24 December 2018.
  7. ^ "Prostatitis". NHS. 19 October 2017. Retrieved 24 December 2018.
  8. ^ a b Wang RC, Smith-Bindman R, Whitaker E, Neilson J, Allen IE, Stoller ML, et al. (March 2017). "Effect of Tamsulosin on Stone Passage for Ureteral Stones: A Systematic Review and Meta-analysis". Annals of Emergency Medicine. 69 (3): 353–361.e3. doi:10.1016/j.annemergmed.2016.06.044. PMID 27616037.
  9. ^ a b c British national formulary: BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 767. ISBN 9780857113382.
  10. ^ Hutchison LC, Sleeper RB (2010). Fundamentals of Geriatric Pharmacotherapy: An Evidence-Based Approach. ASHP. p. 209. ISBN 9781585283057.
  11. ^ "The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.
  12. ^ "Tamsulosin Drug Usage Statistics, United States, 2013 - 2022". ClinCalc. Retrieved 30 August 2024.

Previous Page Next Page






تامسولوسين Arabic تامسولوسین AZB Tamsulosina Catalan Tamswlosin CY Tamsulosin German Ταμσουλοσίνη Greek Tamsulosina Spanish تامسولوسین FA Tamsulosine French Tamsulosin ID

Responsive image

Responsive image