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ChEMBL
 | |
| Content | |
|---|---|
| Description | Biological database |
| Data types captured | Molecules with drug-like properties and biological activity |
| Contact | |
| Research center | European Molecular Biology Laboratory |
| Laboratory |  European Bioinformatics Institute |
| Authors | Andrew Leach, Team Leader 2016-Present; John Overington, Team Leader 2008-2015 |
| Primary citation | PMID 21948594 |
| Release date | 2009 |
| Access | |
| Website | ChEMBL |
| Download URL | Downloads |
| Web service URL | ChEMBL Webservices |
| Sparql endpoint | ChEMBL EBI-RDF Platform |
| Miscellaneous | |
| License | The ChEMBL data is made available on a Creative Commons Attribution-Share Alike 3.0 Unported Licence |
| Versioning | ChEMBL_28 |
ChEMBL or ChEMBLdb is a manually curated chemical database of bioactive molecules with drug inducing properties.[1] It is maintained by the European Bioinformatics Institute (EBI), of the European Molecular Biology Laboratory (EMBL), based at the Wellcome Trust Genome Campus, Hinxton, UK.
The database, originally known as StARlite, was developed by a biotechnology company called Inpharmatica Ltd. later acquired by Galapagos NV. The data was acquired for EMBL in 2008 with an award from The Wellcome Trust,[2] resulting in the creation of the ChEMBL chemogenomics group at EMBL-EBI, led by John Overington.[3][4]
- ^ Gaulton, A; et al. (2011). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Research. 40 (Database issue): D1100-7. doi:10.1093/nar/gkr777. PMC 3245175. PMID 21948594.
- ^ "Open access drug discovery database launches with half a million compounds | Wellcome". wellcome.ac.uk. 18 January 2010. Retrieved 31 August 2019.
- ^ Bender, A (2010). "Databases: Compound bioactivities go public". Nature Chemical Biology. 6 (5): 309. doi:10.1038/nchembio.354.
- ^ Overington J (April 2009). "ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI). Interview by Wendy A. Warr". J. Comput.-Aided Mol. Des. 23 (4): 195–8. Bibcode:2009JCAMD..23..195W. doi:10.1007/s10822-009-9260-9. PMID 19194660. S2CID 2946417.
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