Casirivimab/imdevimab

Infotaula de fàrmacCasirivimab/imdevimab
REGN10933 (blau) i REGN10987 (taronja) units a la proteïna S del SARS-CoV-2 (rosa).
Malaltia objecteCOVID-19 Modifica el valor a Wikidata
DrugBankDB15691 Modifica el valor a Wikidata

Casirivimab/imdevimab és un medicament experimental desenvolupat per l'empresa nord-americana de biotecnologia Regeneron Pharmaceuticals. Es tracta de la barreja de dos anticossos monoclonals, casirivimab (REGN10933) i imdevimab (REGN10987),[1][2] combinació destinada a atacar al coronavirus SARS-CoV-2 responsable de la COVID-19.[3][4] Combinació destinada a evitar la fugida mutacional.[5]

  1. Morelle, Rebecca «Antibody treatment to be given to Covid patients». BBC News Online, 14-09-2020.
  2. «Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for Hospitalized Adult Patients With COVID-19», 03-09-2020.
  3. Kelland, Kate «Regeneron's antibody drug added to UK Recovery trial of COVID treatments». Reuters, 14-09-2020.
  4. «Regeneron's COVID-19 Response Efforts».
  5. «Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies». Science, 369, 6506, 8-2020, pàg. 1014–1018. DOI: 10.1126/science.abd0831. PMC: 7299283. PMID: 32540904.

Casirivimab/imdevimab

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