KCNH2

KCNH2
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1BYW, 1UJL, 2L0W, 2L1M, 2L4R, 2LE7, 4HP9, 4HQA, 2N7G
Dynodwyr
Cyfenwau	KCNH2, ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1, potassium voltage-gated channel subfamily H member 2
Dynodwyr allanol	OMIM: 152427 HomoloGene: 201 GeneCards: KCNH2
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• potassium channel activity; • protein homodimerization activity; • scaffold protein binding; • voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization; • C3HC4-type RING finger domain binding; • voltage-gated ion channel activity; • ion channel activity; • GO:0001948, GO:0016582 protein binding; • identical protein binding; • voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization; • voltage-gated potassium channel activity; • phosphorelay sensor kinase activity; • ubiquitin protein ligase binding; • delayed rectifier potassium channel activity; • inward rectifier potassium channel activity;
Cydrannau o'r gell	• integral component of membrane; • bilen; • voltage-gated potassium channel complex; • Cellbilen; • cell surface; • perinuclear region of cytoplasm; • inward rectifier potassium channel complex; • integral component of plasma membrane;
Prosesau biolegol	• membrane depolarization during action potential; • cardiac muscle contraction; • GO:0072468 signal transduction; • regulation of membrane potential; • regulation of ion transmembrane transport; • ventricular cardiac muscle cell action potential; • cludo ïon; • potassium ion export across plasma membrane; • potassium ion transport; • membrane repolarization during action potential; • potassium ion homeostasis; • regulation of heart rate by hormone; • transmembrane transport; • potassium ion transmembrane transport; • positive regulation of potassium ion transmembrane transport; • phosphorelay signal transduction system; • regulation of membrane repolarization; • negative regulation of potassium ion transmembrane transport; • membrane repolarization during cardiac muscle cell action potential; • regulation of heart rate by cardiac conduction; • regulation of potassium ion transmembrane transport; • regulation of ventricular cardiac muscle cell membrane repolarization; • membrane repolarization during ventricular cardiac muscle cell action potential; • membrane repolarization; • negative regulation of potassium ion export across plasma membrane; • potassium ion import across plasma membrane; • cardiac conduction;
	Sources:Amigo / QuickGO
Orthologau
	3757
	n/a
	ENSG00000055118
	n/a
	Q12809
	n/a
	NM_000238; NM_001204798; NM_172056; NM_172057
	n/a
	NP_000229; NP_001191727; NP_742053; NP_742054
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn KCNH2 yw KCNH2 a elwir hefyd yn Potassium voltage-gated channel subfamily H member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7q36.1.^[2]

[1] "Human PubMed Reference:".

[2] KCNH2 - Cronfa NCBI

[1]

[2]

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KCNH2

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